Enzyme molecular engineering and catalysis

Objectives

Discovery, improvement and rational exploitation of high performance enzymatic biocatalysts based upon structure-function analysis.

 

Efficient synthesis of novel products:

 

Integrated use of  microbiology, metagenomics and data mining coupled to molecular biology and 3D modelling

 

Rational enzyme engineering and directed molecular evolution

 

Molecular modelling and computational design of proteins / redesign enzyme specificity and activity for non native substrates and non existing reactions

 

 

 

Technological expertise:

in production, enzyme stability and immobilisation in both batch and continuous reactors

 

Team: