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Mickaël CASTELAIN

Mickaël CASTELAIN
Research Associate INRA
Metabolic Analysis of Procaryotes
+33 (0) 5 67 04 88 01
INSA de Toulouse
135 avenue de Rangueil
31077 Toulouse cedex 4 - FRANCE
mickael.castelain@insa-toulouse.fr

 

 

CV

2003

2004

 

2007

 

B.Sc. Physics (University of Toulon, France)

M.Sc. Rheology, Mechanics and Physics of Fluid Materials (Grenoble Institute of Technology / Laboratoire de Rhéologie, France)

Ph.D. Rheology, Mechanics and Physics of Fluid Materials (Grenoble Institute of Technology / Laboratoire de Rhéologie, France)

Oct.'04-Oct.'07

Ph.D fellow in the Laboratoire de Rhéologie, Grenoble, France

Fev.'08-Fev.'09

FRM-supported Post-Doc researcher at the Department of Physics, Umeå, Sweden.

Fev.'09-Nov'10

Post-Doc researcher from the Faculty of Science & Tech, Department of Physics, Umeå, Sweden.

Nov'10-present

Tenure-track position as Junior Researcher Scientist at "Laboratoire d'Ingénierie des Procédés et Systèmes Biologiques" INSA, Toulouse, France.

 

 

RESEARCH TOPICS

My research interests are focused on understanding mechanisms governing acid lactic bacteria adhesion on intestinal mucus. Particular efforts are invested towards in vitro approach such as mucus-secreting cell lines and local rheology of the mucosal gel.
How and why strains can persist within the intestinal tract? Would biological determinant interfere and lead such persistence? Those are questions that some biophysical approaches would address from the population of bacteria scale to the molecular level of such process.


Expertise / interest can be listed as follows:

  • Cell cultures (procaryotes and eucaryotes)
  • Microscopy (fluorescence etc.)
  • Optical designs
  • Optical tweezers and force spectroscopy (Single-Molecule techniques)
  • Molecular biology (mutants contructs, cloning/expression/purification)
  • Microrheology (harmonic and particle tracking)
  • …to be continued…

Full up-to-date list of publications here

 

 

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