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Jérome Morchain

 

Jérôme MORCHAIN
Maître de Conférences / Assistant Professor
Transfert Interface Mélange
+33 (0) [561559774]
INSA de Toulouse
135 avenue de Rangueil
31077 Toulouse cedex 4 - FRANCE
jerome.morchain @ insa-toulouse.fr

 

CV

nov 2103 : Habilitation à Diriger des Recherches
depuis 2003 : Maître de Conférences INSA Toulouse

2002 - 2003 : Ingénieur de Recherche RHODIA
Morchain, J., 2000. Etude et modélisation des couplages entre cinétiques physiques et biologiques dans les réacteurs de grand volume.

2000 : Docteur de l’INSA Toulouse en Microbiologie

1996 : Diplôme d’Etudes Approfondies « Physique et Chimie de l’Environnement »

1995 : Ingénieur de l’Ecole Nationale d’Ingénieur de Génie Chimique de Toulouse

 

RESEARCH TOPICS

Mixing, Stirred tanks, Hydrodynamics-Biology interactions
Modelling of bioreactors: coupling mixing, gas-liquid mass transfer, biological reaction through kinetic, metabolic, population balance approaches.
Interactions between physical phenomena and biological response.
Computational Fluid Dynamics (RANS, LES, DNS)

 

TEACHING

Mécanique des fluides
Modélisation et simulation des procédés
Analyse numérique
Systèmes linéaires
Agitation Mélange Micromélange

 

Habilitation a Diriger des recherches

Modélisation des bioréacteurs par approche couplée de la mécanique des Fluides et des bilans de population.

Rapporteurs (O. Bernard, J. Pruvost, D. Marchisio)

PuBLICATIONS

[1] Mate, A., Morchain, J., Masbernat, O., Gourdon, C., 1996a. A transient method for the study of wetting in a liquid-liquid contactor. Chemical Engineering Science 51, 5313–5323.

[2] Morchain, J., Maranges, C., Fonade, C., 2000b. CFD modelling of a two-phase jet aerator under influence of a crossflow. Water Research 34, 3460–3472.

[3] Fonade, C., Doubrovine, N., Maranges, C., Morchain, J., 2001a. Influence of a transverse flowrate on the oxygen transfer performance in heterogeneous aeration: case of hydro-ejectors. Water Research 35, 3429–3435.

[4] Augier, F., Morchain, J., Guiraud, P., Masbernat, O., 2003b. Volume fraction gradient-induced flow patterns in a two-liquid phase mixing layer. Chemical Engineering Science 58, 3985–3993.

[5] Delafosse, A., Liné, A., Morchain, J., Guiraud, P., 2008a. LES and URANS simulations of hydrodynamics in mixing tank: Comparison to PIV experiments. Chemical Engineering Research and Design 86, 1322–1330.

[6] Morchain, J., Fonade, C., 2009. A structured model for the simulation of bioreactors under transient conditions. AIChE J. 55, 2973–2984.

[8] Delafosse, A., Morchain, J., Guiraud, P., Liné, A., 2009b. Trailing vortices generated by a Rushton turbine: Assessment of URANS and large Eddy simulations. Chemical Engineering Research and Design 87, 401–411.

[7] Huchet, F., Liné, A., Morchain, J., 2009b. Evaluation of local kinetic energy dissipation rate in the impeller stream of a Rushton turbine by time-resolved PIV. Chemical Engineering Research and Design 87, 369–376.

[8] Siangsanun, V., Guigui, C., Morchain, J., Marteil, P., Levecq, C., Puprasert, C., Hébrard, G., 2011. Velocity measurement in the hydrocyclone by oil droplet, doppler ultrasound velocimetry, and CFD modelling. Can. J. Chem. Eng. 89, 725–733.

[9] Douaire, M., Mercade, M., Morchain, J., Loubière, P., 2011. A unique phenotypic modification of Lactococcus lactis cultivated in a couette bioreactor. Biotechnol. Bioeng. 108, 559–571.

[10] Morchain, J., Douaire, M., Mercade, M., Loubière, P., 2011. What can flow induce in bacteria? Biotechnology and Bioengineering 108, FMvi.

[11] Gabelle, J.-C., Augier, F., Carvalho, A., Rousset, R., Morchain, J., 2011. Effect of tank size on kLa and mixing time in aerated stirred reactors with non-newtonian fluids. Can. J. Chem. Eng. 89, 1139–1153.

[12] Mercier-Bonin, M., Dehouche, A., Morchain, J., Schmitz, P., 2011a. Orientation and detachment dynamics of Bacillus spores from stainless steel under controlled shear flow: Modelling of the adhesion force. International Journal of Food Microbiology 146, 182–191.

[13] Paule, A., Lauga, B., Ten-Hage, L., Morchain, J., Duran, R., Paul, E., Rols, J.L., 2011a. A photosynthetic rotating annular bioreactor (Taylor-Couette type flow) for phototrophic biofilm cultures. Water Research 45, 6107–6118.

[14] Boulbene, B., Morchain, J., Bonin, M.M., Janel, S., Lafont, F., Schmitz, P., 2012b. A combined computational fluid dynamics (CFD) and experimental approach to quantify the adhesion force of bacterial cells attached to a plane surface. AIChE J., 58, 3614-3624.

[15] Gabelle, J.-C., Jourdier, E., Licht, R.B., Ben Chaabane, F., Henaut, I., Morchain, J., Augier, F., 2012. Impact of rheology on the mass transfer coefficient during the growth phase of Trichoderma reesei in stirred bioreactors. Chemical Engineering Science 75, 408–417.

[16] Linkès, M., Martins Afonso, M., Fede, P., Morchain, J., Schmitz, P., 2012. Numerical study of substrate assimilation by a microorganism exposed to fluctuating concentration. Chemical Engineering Science, 81, 8–19.

[17] Morchain, J., Gabelle, J.-C., Cockx, A., 2013. Coupling of biokinetic and population balance models to account for biological heterogeneity in bioreactors. AIChE J. 59, 369–379.

 [18] Gabelle J-C, Morchain J, Anne-Archard D, Augier F, Liné A., 2013. Experimental determination of the shear rate in a stirred tank with a non-newtonian fluid: Carbopol. AIChE J., 59, 2251-2266

[19]  Morchain, J., Gabelle, J.-C., Cockx, A., 2013. A Coupled Population Balance Model and CFD Approach for the Simulation of Mixing Issues in Lab-scale and Industrial Bioreactors. AIChE Journal. Accessible online


PhD Supervision


Delafosse, A., 2008 Analyse et étude numérique des effets de mélange dans un bioreacteur
Douaire, M., 2010. Etude expérimentale et numérique de la réponse de lactococcus Lactis NCDO2118 aux conditions hydrodynamiques locales en réacteur Couette.
Gabelle, J.-C., 2012 Analyse locale et globale de l'hydrodynamique et du transfert de matière dans des fluides à rhéologie complexe caractéristiques des milieux de fermentation
Linkès, M., 2012 Simulation numérique et modélisation de l’assimilation de substrats par des micro-organismes au sein d’un écoulement turbulent


International Conferences


Morchain, J., Maranges, C., Fonade, C., 1999a. Modelling and numerical simulation of couplings between physical and biological kinetics in heterogeneous reactors, in: 2nd European Congress of Chemical Engineering. Montpellier, FRANCE.
Augier, F., Morchain, J., Guiraud, P., Masbernat, O., 2001. Volume fraction gradients induced flow patterns in a liquid-liquid mixing-layer, in: 4th Internationnal Conference on Multiphase Flow. New-Orleans, Louisiane, U.S.A.
Huchet, F., Liné, A., Morchain, J., 2009c. Evaluation of local kinetic energy dissipation rate in the impeller stream of a Rushton turbine by time-resolved PIV, in: 13th European Conference on Mixing. London.
Douaire, M., Morchain, J., Liné, A., 2009. Mini review: relationship between hydrodynamic conditions and substrate influx toward cells, in: 13th European Conference on Mixing. London.
Douaire, M., Morchain, J., Loubière, P., 2009a. A coupled numerical and experimental study of micromixing in a batch bioreactor, in: 14th European Congress on Biotechnology. Barcelona, Spain.
Siangsanun, V., Puprasert, C., Guigui, C., Morchain, J., Marteil, P., Bréant, P., Levecq, C., Hébrard, G., 2009. Velocity measurement in hydrocyclone by oil droplet method, döppler ultrasound velocimetry and CFD modeling, in: CFD in Chemical Engineering and Industrial Processes Symposium. Montréal, QUEBEC.
Delafosse, A., Liné, A., Morchain, J., Guiraud, P., 2008b. LES and RANS simulations of hydrodynamics in mixing tank: comparison to PIV experiments, in: 6th International Symposium on Mixing in Industrial Process. Niagara on the lake, Ontario, CANADA.
Delafosse, A., Morchain, J., Guiraud, P., 2009. Mixing study in a bioreactor by LES and particle tracking, in: 8th World Congress of Chemical Engineering. Montréal, QUEBEC.
Delafosse, A., Morchain, J., Guiraud, P., Liné, A., 2009a. Trailing vortices generated by a Rushton turbine: Assessment of URANS and large Eddy simulations, in: 13th European Conference on Mixing. London.
Douaire, M., Loubière, P., Morchain, J., 2010. Cultures of Lactococcus lactis NCDO2118 in a Taylor-Couette reactor: a case study, in: 19th CHISA & 7th European Congress of Chemical Engineering - ECCE-7. Praga.
Gabelle, J.-C., Augier, F., Rousset, R., Morchain, J., Liné, A., 2010. Effect of rheology on kLa and mixing time in 42&340L stirred reactors, in: North American Mixing Forum, Mixing XXII. Victoria, Canada.
Morchain, J., Gabelle, J.-C., Cockx, A., 2012. A combination of population balance and kinetic models for bioreactor scale-up using CFD. XXIII North American Mixing Forum, Playa Del Carmen, Mexico.


Conférences Nationales


Prat, L., Gourdon, C., Morchain, J., Rigal, L., 2002. Transport d’un mélange polyphasique matière végétale-solvant dans un extrudeur bivis. Simulateur dynamique et validation expérimentale, in: SIMO.
Morchain, J., Uribelarrea, J.-L., Roux, G., Fonade, C., 1999. Intégration de la modélisation des réactions biologiques dans une description de l’écoulement basée sur la mécanique des fluides numérique, in: GRUTTEE.
Morchain, J., Maranges, C., Fonade, C., 1999b. Simulation numérique du transfert d’oxygène dans un jet diphasique sous l’influence d’un courant transversal, in: 14ième Congrès Français De Mécanique. Toulouse, FRANCE.
Morchain, J., 2009. Instantaneous substrate uptake rate calculation from dynamic simulation of mass transfer toward a living cell, in: Congrès Français De Génie Des Procédés, Récents Progrès En Génie Des Procédés. Ed. SFGP, Marseille.
Douaire, M., Morchain, J., Loubière, P., 2009b. Experimental study of energy dissipation rate effect on Lactococcus lactis batch culture in a Couette reactor., in: Congrès Français De Génie Des Procédés. Marseille.
Douaire, M., Morchain, J., Loubière, P., 2009c. Réponse de Lactococcus lactis NCDO 2118 aux conditions de mélange dans un réacteur Couette, in: Club Français Des Bactéries Lactiques. Toulouse.
Haouech, L., Cockx, A., Morchain, J., Sayeb, E., Spérandio, M., 2009. Waste water treatment in an oxidation ditch: spatio-temporal variation of oxygen concentration with biological activity, in: Congrès Français De Génie Des Procédés. Marseille.