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Publications

2019

Enzyme-fusion strategies for redirecting and improving carotenoid synthesis in S. cerevisiae - Hery Rabeharindranto, Sara Castaño-Cerezo, Thomas Lautier, Luis F. Garcia-Alles, Christian Treitz Andreas Tholey, Gilles Truan - Metabolic Engineering Communications - https://doi.org/10.1016/j.mec.2019.e00086

 

2018 

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450.    Campelo D, Esteves F, Brito Palma B, Costa Gomes B, Rueff J, Lautier T, Urban P, Truan G, Kranendonk M. - Int J Mol Sci. 2018 Dec 6;19(12). pii: E3914. doi: 10.3390/ijms19123914. - PMID:30563285

 

Accurate Determination of Human CPR Conformational Equilibrium by smFRET using Dual Orthogonal Non-Canonical Amino Acid Labeling. - Quast RB, Fatemi F, Kranendonk M, Margeat E, Truan G. - Chembiochem. 2018 Nov 14. doi: 10.1002/cbic.201800607. [Epub ahead of print] - PMID: 30427570

 

Human cytochrome P450 expression in bacteria: Whole-cell highthroughput activity assay for CYP1A2, 2A6 and 3A4 -  Francisco Estevesa, Diana Campeloa, Philippe Urbanb, Sophie Bozonnetb, Thomas Lautierb, José Rueffa, Gilles Truanb, Michel Kranendonk - Biochemical Pharmacology 158 (2018) 134–140 

 

Ligand Access Channels in Cytochrome P450 Enzymes: A Review - Philippe Urban Thomas Lautier Denis Pompon Gilles Truan Int. J. Mol. Sci. 2018 19  https://doi.org/10.3390/ijms19061617

 

INRA's research in industrial biotechnology: For food, chemicals, materials and fuels - Carole Camarasa ;  Hubert Chiron ;  Fayza Daboussi ; Guy Della Valle ; Claire Dumas ; Vincent Farines ; Juliane Floury ; Valerie Gagnaire;  Nathalie Gorret; Joelle Léonil Jean-Roch Mouret Michael O'Donohue Jean-Marie Sablayrolles ; Jean-Michel Salmon ; Luc Saulnier  ; Gilles Truan -  Innovative Food Science and Emerging Technologies, Elsevier, 2018, 46, pp.140-152. DOI : 10.1016/j.ifset.2017.11.008

 

Adaptive response of yeast cells to triggered toxicity of phosphoribulokinase - Catherine Rouzeau, Adilya Dagkesamanskaya, Krzysztof Langer  Jerome Bibette, Jean Baudry, Denis Pompon , Veronique Anton-Leberre - Research in Microbiology -  https://doi.org/10.1016/j.resmic.2018.06.002

 

2017

N.C.T. Tram, N.T. Son, N. Thi Nga, V.T.T. Phuong, N. Thi Cuc, D. Thi Phuong, G. Truan, N.M. Cuong, D. Thi Thao, The hepatoprotective activity of a new derivative kaempferol glycoside from the leaves of Vietnamese Phyllanthus acidus (L.) Skeels, Med. Chem. Res. (2017). doi:10.1007/s00044-017-1914-x.

 

D. Campelo, T. Lautier, P. Urban, F. Esteves, S. Bozonnet, G. Truan, M. Kranendonk, The hinge segment of human NADPH-cytochrome P450 reductase in conformational switching: the critical role of ionic strength, accepted with minor revisions in Front. Pharmacol. (2017).
 
L.F. Garcia-Alles, E. Lesniewska, K. Root, N. Aubry, N. Pocholle, C. Mendoza, E. Bourillot, K. Konstantin, D. Pompon, R. Zenobi, D. Reguera, G. Truan*, Spontaneous non-canonical assembly of CcmK hexameric components from carboxysome shells of cyanobacteria, accepted in PLoS One (2017).
 
D. Pompon, L. F. Garcia Alles, G. Truan. Nanotechnology for Synthetic Biology: Crossroads Throughout Spatial Confinement, in: M.A. Axelos, M. H. Van de Vorde (Eds.), Nanotechnol. Agric. Food Sci., Wiley-VCH Verlag GmbH & Co. KGaA, 2017: pp. 209–234.

 

2016

T. Lautier, P. Urban, J. Loeper, L. Jezequel, D. Pompon, G. Truan. Ordered chimerogenesis applied to CYP2B P450 enzymes, Biochim. Biophys. Acta Gen. Subj. 1860 (2016) 1395–1403.

 

B.B. Palma, D. Moutinho, P. Urban, J. Rueff, M. Kranendonk, Cytochrome P450 expression system for high-throughput real-time detection of genotoxicity: Application to the study of human CYP1A2 variants, Mutat. Res. Toxicol. Environ. Mutagen. 806 (2016) 24–33.

2015

Carquet, D. Pompon, G. Truan. Transcription interference and ORF nature strongly affect promoter strength in a reconstituted metabolic pathway, Front. Bioeng. Biotechnol. 3 (2015) 21.


O. Frances, F. Fatemi, D. Pompon, E. Guittet, C. Sizun, J. Pérez, E. Lescop, G. Truan. A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase, Biophys. J. 108 (2015) 1527–1536.


P. Urban, G. Truan, D. Pompon. Access channels to the buried active site control substrate specificity in CYP1A P450 enzymes, Biochim. Biophys. Acta Gen. Subj. 1850 (2015) 696–707.


J.J. Stegeman, L. Behrendt, B.R. Woodin, A. Kubota, B. Lemaire, D. Pompon, J.V. Goldstone, P. Urban, Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast, Biochim. Biophys. Acta Gen. Subj. 1850 (2015) 2340–2352.